Monday, February 20, 2012

Two people of normal health have a child with hemophilia (sex-linked recessive)?

What are the genotypes of both parents? ExplainTwo people of normal health have a child with hemophilia (sex-linked recessive)?The parents are heterozygous for hemophilia. In order for the child to have it, he/she would have to inherit 1 copy of the recessive gene from each parent, otherwise the trait would be masked by the non-hemophilia gene.Two people of normal health have a child with hemophilia (sex-linked recessive)?Dad has X (normal) y



Mom has X (normal) X(hemophelia)



The child is a boy



the boy's genotype is X (hemophelia) YTwo people of normal health have a child with hemophilia (sex-linked recessive)?H=Hemophilia

n=Normal



Dad=Xn y

Mom=XH Xn



Unless you know that the dad is affected by the disease (in which case he probably wouldn't be having a child), the faulty gene comes entirely from the mother. Since the Hemophilia gene is recessive the mother won't have any symptoms of the disease. The problem is: 50% of this couples male children will have the disease, and 25% of their total children will have it, and 25% of the female children will be carriers.

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